OUR PERSPECTIVE
Shortcomings of existing therapies
Current standard of care treatments are ineffective for millions worldwide.
Limited Efficacy
Slow onset – Up to 3 months or more for SSRIs to take full effect
Trial and error – Remission with first selected SSRI occurs only 30% of the time
Low response rate – Only 50% respond within 8 weeks and 33% become treatment-resistant
High relapse rate – Estimated that 40-60% of patients with SUD return to active addiction
Side Effects
Addiction – 10-15% of benzodiazepine users become addicted
Sexual dysfunction – 55% of patients on SSRIs experience sexual dysfunction
Weight gain – Depending on the drug, patients on SSRIs gain on average 16-24lbs over 12 months
Sleep – SSRIs interfere with sleep architecture, potentially complicating the sleep of depressed patients
Our unique approach
Compounds with prior evidence in humans
To minimize development risk, we focus on compounds that have previously been used in humans and have established safety profiles.


Enabling platform technologies


Decentralized drug development
In addition to funding, our evolving companies have access to our deep domain expertise and operational backbone.


Learn more about our approach
OUR MODELWHERE WE’RE HEADED
Our technologies drive efficient drug discovery and improved treatment outcomes.
Our unique model combines funding with operational expertise to develop innovative and impactful CNS therapeutics.
OUR MODELNews & Insights
Press Release
atai Life Sciences to Collaborate with Massachusetts General Hospital to Accelerate Discovery of Mechanisms Underlying Therapeutic Effects of Psychedelic Agents
atai Life Sciences, a global biotech company developing psychedelic and non-psychedelic compounds for various mental health indications, today announced it…
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atai Life Sciences Acquires Majority Stake in Recognify Life Sciences to Develop Novel Treatment for Cognitive Impairment Associated with Schizophrenia
atai Life Sciences, a clinical-stage biopharmaceutical company aiming to transform the treatment of mental health disorders, today announced that it…
Press Release
atai Life Sciences Appoints New Chief Financial Officer and Chief Medical Officer
atai Life Sciences, a global biotech company developing psychedelic and non-psychedelic compounds for various mental health indications, has announced the…